New Measurement Method of Wound Healing by Stereoimage Optical Topometer System.
- Author:
Kyoung Hwan RHO
1
;
Seung Kyu HAN
;
Woo Kyung KIM
Author Information
1. Department of Plastic Surgery, Korea University College of Medicine, Seoul, Korea. pshan@kumc.or.kr
- Publication Type:Case Report
- Keywords:
Wound healing;
Stereoimage optical topometer
- MeSH:
Animals;
Biopsy;
Mice;
Organothiophosphorus Compounds;
Wound Healing
- From:Journal of the Korean Society of Plastic and Reconstructive Surgeons
2008;35(6):755-758
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: In order to determine the amount of wound healing, objective sequential assessments of changes in wound size and depth are essential. Although a variety of measurements for wound healing have been proposed, a gold standard for quantifying day-to-day changes in healing has not been established. We present here a simple and non-invasive wound measurement method that quantitatively and accurately documents changes of the size of a raw surface and the volume of a soft tissue defect using a stereoimage optical topometer(SOT) system. METHODS: Using a 5mm diameter biopsy punch, four circular wounds were created on abdominal area of a diabetic mouse. Photographs were taken using SOT system at baseline, 5th day and 10th postoperative day. The wound margin was traced on a digitalized photo and evaluated the area and the volume of the wound by SOT system. RESULTS: The SOT system calculated a mean wound surface of 15.93+/-0.29mm2 and volume of 827.50+/-88.86 intensity/pixel x area(I/PA) immediately after wounding. On the 5th day after the operation wound surface declined by 10.73mm2 and on the 10th day declined by 5.95mm2. The wound volume also declined from 827.50 I/PA to 161.75 I/PA and 30.50 I/PA on 0, 5th and 10th day, respectively. CONCLUSION: The SOT system described in this study represents a reliable, simple, practical, and non-invasive technique to accurately monitor and evaluate wound healing.
