A case of leukemoid reaction in a patient with sarcomatous hepatocellular carcinoma.
10.3350/kjhep.2011.17.3.226
- Author:
Hyun Phil SHIN
1
;
Jung Won JEON
;
Jae Jun PARK
;
Jae Myung CHA
;
Kwang Ro JOO
;
Joung Il LEE
;
Gou Young KIM
;
So Young KANG
Author Information
1. Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University, Seoul, Korea. megadoctor@medimail.co.kr
- Publication Type:Case Report
- Keywords:
Leukemoid reaction;
Paraneoplastic;
Hepatocellular carcinoma
- MeSH:
Aged;
Biopsy, Fine-Needle;
Carcinoma, Hepatocellular/*pathology;
Humans;
Leukemoid Reaction/*diagnosis;
Leukocyte Count;
Liver Neoplasms/*pathology;
Male;
Tomography, X-Ray Computed
- From:The Korean Journal of Hepatology
2011;17(3):226-228
- CountryRepublic of Korea
- Language:English
-
Abstract:
A leukemoid reaction is defined as reactive leukocytosis exceeding 50,000/mm3, with a significant increase in early neutrophil precursors, and can be a paraneoplastic manifestation of various malignant tumors. A 71-year-old male patient complained of decreased appetite, fatigue, and abdominal fullness. He had a palpable, firm liver, and laboratory investigations suggested leukemoid reaction. Liver dynamic computed tomography revealed a hypervascular mass, and an ultrasound-guided fine-needle aspiration of the mass confirmed hepatocellular carcinoma (HCC) with a sarcomatoid component. The leukocyte count of the patient had increased to 147,800/mm3, and he died 10 days after admission. This is a rare case of leukemoid reaction in a patient with sarcomatous HCC.