A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage.
10.3350/kjhep.2011.17.3.229
- Author:
Ju Seung KIM
1
;
Young Rock JANG
;
Ji Won LEE
;
Jin Yong KIM
;
Young Kul JUNG
;
Dong Hae CHUNG
;
Oh Sang KWON
;
Yun Soo KIM
;
Duck Joo CHOI
;
Ju Hyun KIM
Author Information
1. Department of Internal Medicine, Gachon University Gil Hospital, Gachon University of Medicine and Science, Incheon, Korea. 93cool@hanmail.net
- Publication Type:Case Report
- Keywords:
Drug-induced liver injury;
Amoxicillin;
Cholestatic hepatitis
- MeSH:
Actinomycosis/drug therapy;
Adult;
Alanine Transaminase/blood;
Alkaline Phosphatase/blood;
Amoxicillin/*adverse effects;
Anti-Bacterial Agents/*adverse effects;
Aspartate Aminotransferases/blood;
Cholestasis/*chemically induced;
Drug-Induced Liver Injury/*diagnosis/etiology;
Female;
Humans;
Liver/enzymology
- From:The Korean Journal of Hepatology
2011;17(3):229-232
- CountryRepublic of Korea
- Language:English
-
Abstract:
Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present a case of a 39-year-old woman who was diagnosed with abdominal actinomycosis and received amoxicillin treatment. The patient displayed hepatocellular and bile-duct injury, in addition to elevated levels of liver enzymes. The patient was diagnosed with amoxicillin-induced cholestatic hepatitis. When amoxicillin was discontinued, the patient's symptoms improved and her liver enzyme levels reduced to near to the normal range.
