Unmasking Granulomatous Pneumocystis jirovecii Pneumonia with Nodular Opacity in an HIV-Infected Patient after Initiation of Antiretroviral Therapy.
10.3349/ymj.2016.57.4.1042
- Author:
Hyung Woo KIM
1
;
Jung Yeon HEO
;
Yong Moon LEE
;
S J KIM
;
Hye Won JEONG
Author Information
1. Division of Infectious Diseases, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea. jyeon78@naver.com
- Publication Type:Case Reports
- Keywords:
Pneumocystis pneumonia;
HIV infections;
immune reconstitution inflammatory syndrome
- From:Yonsei Medical Journal
2016;57(4):1042-1046
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pneumocystis jirovecii pneumonia (PJP) in patients with HIV infection can, in rare cases, present with pulmonary nodules that histologically involve granulomatous inflammation. This report describes an intriguing case of granulomatous PJP with pulmonary nodules after commencing antiretroviral therapy (ART) in an HIV-infected patient without respiratory signs or symptoms. Diagnosis of granulomatous PJP was only achieved through thoracoscopic lung biopsy. This case suggests that granulomatous PJP should be considered in the differential diagnosis of pulmonary nodules in HIV-infected patients for unmasking immune reconstitution inflammatory syndrome manifestation after initiation of ART.
