Four patients with hepatitis A presenting with fulminant hepatitis and acute renal failure and who underwent liver transplantation.
10.3350/kjhep.2009.15.3.362
- Author:
Se Hoon OH
1
;
Joon Hyoek LEE
;
Ji Won HWANG
;
Hye Young KIM
;
Chang Hoon LEE
;
Geum Youn GWAK
;
Moon Seok CHOI
;
Kwang Chul KOH
;
Seung Woon PAIK
;
Byung Chul YOO
Author Information
1. Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea. liverjhlee@skku.edu
- Publication Type:Case Report ; English Abstract
- Keywords:
Hepatitis A;
Fulminant hepatitis;
Acute renal failure;
Liver transplantation
- MeSH:
Adult;
Age Factors;
Female;
Hepatitis/complications/*diagnosis/therapy;
Hepatitis A/complications/*diagnosis;
Hepatomegaly/diagnosis/etiology;
Humans;
Kidney Failure, Acute/complications/*diagnosis;
Liver/pathology;
Liver Cirrhosis/diagnosis/etiology;
*Liver Transplantation;
Male;
Tomography, X-Ray Computed
- From:The Korean Journal of Hepatology
2009;15(3):362-369
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hepatitis A is generally known as a mild, self-limiting disease of the liver, but in rare instances it can progress to fulminant hepatitis, which may require liver transplantation for recovery. Such cases are known to be related to old age and underlying liver disease. We report four cases of hepatitis A in which patients presented with fulminant hepatitis and acute renal failure and underwent liver transplantation. The following common features were observed in our cases: (1) occurrence in relatively old age (> or =39 years old), (2) association with acute renal failure, (3) presence of hepatomegaly, and (4) microscopic features of submassive hepatic necrosis.
