Multiple Cancers in a Patient with Systemic Sclerosis and Aggravated Interstitial Lung Disease by Chemotherapy.
10.4046/trd.2013.75.3.111
- Author:
Chan Kwon PARK
1
;
Seok Jong LEE
;
Hyung Jun CHO
;
Kyeong Soo LEE
;
Sung Jun KIM
;
Gu Min CHO
;
Ha Ni LEE
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. ckpaul@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Scleroderma, Systemic;
Lung Neoplasms;
Lung Diseases, Interstitial
- MeSH:
Fibrosis;
Humans;
Leucovorin;
Lung;
Lung Diseases, Interstitial;
Lung Neoplasms;
Organoplatinum Compounds;
Scleroderma, Systemic
- From:Tuberculosis and Respiratory Diseases
2013;75(3):111-115
- CountryRepublic of Korea
- Language:English
-
Abstract:
Although the relationship between malignancy risk with systemic sclerosis (SSc) has been inconclusive, there are some previous studies for a positive correlation. Most patients with SSc have some degree of lung parenchymal involvement in the form of interstitial thickening and fibrosis. Interstitial lung disease is the most common pulmonary manifestation of SSc. Interstitial lung disease following chemotherapy (5-fluorouracil, leucovorin, and oxaliplatin [FOLFOX]) is an uncommon life-threatening complication and it is induced by oxaliplatin. We report a case of multiple cancers in a patient with SSc and aggravated interstitial lung disease by chemotherapy.
