Subcutaneous Phaeohyphomycosis Caused by Phaeoacremonium Species in a Kidney Transplant Patient: The First Case in Korea.
10.3343/kjlm.2011.31.3.201
- Author:
Jonghyeon CHOI
1
;
Yangsoon LEE
;
Hae Sun CHUNG
;
Ja Seung KOO
;
Dongeun YONG
;
Yu Sun KIM
;
Kyungwon LEE
;
Yunsop CHONG
Author Information
1. Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea. deyong@yuhs.ac
- Publication Type:Case Report
- Keywords:
Subcutaneous phaeohyphomycosis;
Phaeoacremonium species;
Renal transplantation;
Immunosuppressive agents
- MeSH:
Antifungal Agents/therapeutic use;
Ascomycota/genetics/*isolation & purification;
Dermatomycoses/drug therapy/etiology/*microbiology;
Fingers/surgery;
Humans;
Immunosuppressive Agents/adverse effects;
*Kidney Transplantation;
Male;
Middle Aged;
Republic of Korea;
Sequence Analysis, DNA;
Subcutaneous Tissue/microbiology
- From:The Korean Journal of Laboratory Medicine
2011;31(3):201-204
- CountryRepublic of Korea
- Language:English
-
Abstract:
Phaeohyphomycosis is a subcutaneous infection caused by dark pigmented fungi, including fungi of the species Phaeoacremonium, Alternaria, Exophiala, and Pyrenochaeta. In August 2005, a 54-yr-old man who had received a renal transplant 5 yr ago was admitted to our hospital with a subcutaneous mass on the third finger of the right hand; the mass had been present for several months. He had been receiving immunosuppressive agents for several years. He underwent excision of the mass, which was followed by aspiration of the wound for bacterial and fungal cultures. Many fungal hyphae were observed on the histology slide treated with periodic acid-Schiff stain. A few white waxy colonies with a woolly texture grew on the Sabouraud dextrose agar at 30degrees C and changed to dark brown in color. Nucleotide sequencing of internal transcribed spacer regions revealed 100% homology to the Phaeoacremonium aleophilum anamorph and Togninia minima teleomorph (514 bp/514 bp). The patient completely recovered after wide surgical excision. Here, we report the first case of phaeohyphomycosis caused by Phaeoacremonium species in a kidney transplant patient in Korea.
