A Case of Gastric Low-grade MALT Lymphoma Induced by a Helicobacter heilmannii-like Organism.
- Author:
Dong Hoon OH
1
;
Nam Hoon KIM
;
Yu Jung CHO
;
Tae Jun SONG
;
Won Ki BAE
;
Kyung Ah KIM
;
June Sung LEE
;
Mee JOO
Author Information
1. Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. n-hkim@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Helicobacter heilmannii;
Helicobacter pylori;
Gastric MALT lymphoma
- MeSH:
2-Pyridinylmethylsulfinylbenzimidazoles;
Adenocarcinoma;
Amoxicillin;
Animals;
Biopsy;
Cats;
Clarithromycin;
Dilatation;
Dogs;
Dyspepsia;
Endoscopy;
Endoscopy, Gastrointestinal;
Follow-Up Studies;
Gastritis;
Helicobacter;
Helicobacter heilmannii;
Helicobacter pylori;
Humans;
Lymphoid Tissue;
Lymphoma;
Lymphoma, B-Cell, Marginal Zone;
Middle Aged;
Peptic Ulcer;
Primates;
Stomach;
Stomach Diseases;
Ulcer
- From:Korean Journal of Gastrointestinal Endoscopy
2011;43(1):25-29
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Helicobacter heilmannii is a Gram negative, long spiral-shaped organism associated with zoonotic infections acquired from primates including cats and dogs. Infection with H. heilmannii leads to gastritis, peptic ulcer disease, gastric adenocarcinoma, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. We experienced a 54-year-old man with dyspepsia who was diagnosed with primary gastric MALT lymphoma (stage IE1) associated with a H. heilmannii-like organism. Upper gastrointestinal endoscopy revealed only microvascular dilatation and mucosal granularity without elevated or ulcerative lesions at the stomach angle. He was probably infected by a pet dog. The man was treated with eradication therapy for 2 weeks including lansoprazole, amoxicillin, and clarithromycin. Four weeks after eradication of the H. heilmannii-like organism, follow-up endoscopy and pathological biopsy findings showed complete remission of the gastric MALT lymphoma.
