A Case of Churg-Strauss Syndrome Manifesting as Colonic Aphthous Ulcers with Granuloma.
- Author:
Jun Sup PARK
1
;
Nam Hoon KIM
;
Joo Hyun PARK
;
Won Ki BAE
;
Jae Won JEONG
;
June Sung LEE
;
Young Soo MOON
;
Mee JOO
Author Information
1. Department of Internal Medicine Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. n-hkim@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Churg-Strauss syndrome;
Colon;
Aphthous ulcer;
Granuloma
- MeSH:
Abdominal Pain;
Asthma;
Churg-Strauss Syndrome;
Colon;
Colon, Sigmoid;
Cyclophosphamide;
Diarrhea;
Eosinophilia;
Eosinophils;
Gastrointestinal Tract;
Granuloma;
Hemorrhage;
Humans;
Laparotomy;
Steroids;
Stomatitis, Aphthous;
Ulcer;
Vasculitis
- From:Korean Journal of Gastrointestinal Endoscopy
2011;43(1):47-51
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Churg-Strauss syndrome is characterized by asthma, peripheral and tissue eosinophilia, extravascular granuloma formation, and vasculitis of multiple organ systems. The gastrointestinal tract may be involved in 20% to 50% of patients, mainly with abdominal pain, diarrhea and GI bleeding. Ulcers in the small and large bowel are an uncommon manifestation, usually detected during laparotomy performed in the setting of bowel perforation. Endoscopically proven segmental colonic aphthous ulcers with typical pathologic findings such as extravascular granuloma formation, eosinophilic infiltration, or vasculitis are a rarer manifestation. We present a patient with Churg-Strauss syndrome and two aphthous ulcers in the sigmoid colon that healed after treatment with high dose steroids and cyclophosphamide.
