Effective Strategies for the Prevention of Nosocomial Sepsis in Extremely Premature Infants.
10.7599/hmr.2009.29.4.354
- Author:
Yun Sil CHANG
1
Author Information
1. Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. yschang@skku.edu
- Publication Type:Review
- Keywords:
Sepsis;
Extremely low birth weight (ELBW);
Nosocomial;
Prevention;
Neonate
- MeSH:
Cross Infection;
Enteral Nutrition;
Hand Hygiene;
Humans;
Incidence;
Infant;
Infant, Extremely Premature;
Infant, Low Birth Weight;
Infant, Newborn;
Intensive Care Units, Neonatal;
Milk, Human;
Quality of Life;
Risk Factors;
Sepsis;
Skin
- From:Hanyang Medical Reviews
2009;29(4):354-361
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nosocomial sepsis or late onset sepsis is among the leading causes of mortality and morbidity in extremely low birth weight infants hospitalized to neonatal intensive care units (NICU). Prevention of nosocomial sepsis is based on strategies that aim to limit susceptibility to infections by enhancing functional maturities, and ameliorating extrinsic risk factors by limiting transmission of organisms and by promoting the judicious use of antimicrobials. Several clinical strategies which are available include; hand hygiene practices; prevention of central venous catheter-related septicemia; judicious use of therapeutic or prophylactic antimicrobials; proper skin care; and early trophic enteral feeding with human milk. The implementation of these proper clinical strategies and maintaining of surveillance system in individual NICU for prevention of nosocomial infection is quite effective and important to reduce the incidence of noscomial sepsis of extremely premature infants and ultimately to improve their survival and quality of life.