Neurological Complications Resulting from Non-Oral Occupational Methanol Poisoning.
10.3346/jkms.2017.32.2.371
- Author:
Ji Hyun CHOI
1
;
Seung Keun LEE
;
Young Eun GIL
;
Jia RYU
;
Kyunghee JUNG-CHOI
;
Hyunjoo KIM
;
Jun Young CHOI
;
Sun Ah PARK
;
Hyang Woon LEE
;
Ji Young YUN
Author Information
1. Department of Neurology, Ewha Womans University School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea. dream-yoon@hanmail.net
- Publication Type:Brief Communication
- Keywords:
Methanol;
Poisoning;
Neurological Manifestations;
Metabolic Encephalopathies
- MeSH:
Acidosis;
Ataxia;
Brain Diseases, Metabolic;
Brain Edema;
Coma;
Eating;
Humans;
Korea;
Methanol*;
Necrosis;
Neurologic Manifestations;
Optic Atrophy;
Parkinsonian Disorders;
Poisoning*;
Renal Dialysis;
Seizures
- From:Journal of Korean Medical Science
2017;32(2):371-376
- CountryRepublic of Korea
- Language:English
-
Abstract:
Methanol poisoning results in neurological complications including visual disturbances, bilateral putaminal hemorrhagic necrosis, parkinsonism, cerebral edema, coma, or seizures. Almost all reported cases of methanol poisoning are caused by oral ingestion of methanol. However, recently there was an outbreak of methanol poisoning via non-oral exposure that resulted in severe neurological complications to a few workers at industrial sites in Korea. We present 3 patients who had severe neurological complications resulting from non-oral occupational methanol poisoning. Even though initial metabolic acidosis and mental changes were improved with hemodialysis, all of the 3 patients presented optic atrophy and ataxia or parkinsonism as neurological complications resulting from methanol poisoning. In order to manage it adequately, as well as to prevent it, physicians should recognize that methanol poisoning by non-oral exposure can cause neurologic complications.
