Pyridoxine responsive sideroblastic anemia in a boy with mitral valve prolapse.
10.3345/kjp.2006.49.11.1223
- Author:
June Seung SUNG
1
;
Ki Hwan KIM
;
Dong Gyun HAN
;
Mi Jeong KIM
;
Young Kook CHO
;
Hae Yul CHUNG
;
Hee Jo BAEK
;
Jae Sook MA
;
Hoon KOOK
;
Tai Ju HWANG
Author Information
1. Department of Pediatrics, Hwasun Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea. hoonkook@chonnam.ac.kr
- Publication Type:Case Report
- Keywords:
Sideroblastic anemia;
Pyridoxine;
Mitral valve prolapse
- MeSH:
Anemia;
Anemia, Hypochromic;
Anemia, Sideroblastic*;
Bone Marrow;
Child, Preschool;
Humans;
Hyperplasia;
Iron Overload;
Male*;
Mitral Valve Prolapse*;
Mitral Valve*;
Mortality;
Pyridoxine*
- From:Korean Journal of Pediatrics
2006;49(11):1223-1226
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sideroblastic anemia is a rare, heterogeneous group of disorders characterized by hyperferremia, microcytic hypochromic anemia, and bone marrow erythroid hyperplasia with the presence of numerous ringed sideroblasts. We describe herewith the case of a rare coincidence of sideroblastic anemia and mitral valve prolapse with resultant regurgitation in a 2-year-old boy. In addition to the inherent propensity for the development of cardiac dysfunction in sideroblastic anemia due to transfusion-associated myocardial iron overload and chronic anemia, a coincidence of MVP will further increase the likelihood of the morbidity or mortality of th patient. in this patient. After response to pyridoxine, the patient remains in good condition with stable hemoglobin levels.
