Histological comparison of endoscopic forceps biopsy with endoscopic mucosal resection in the gastric lesions.
- Author:
Jee Yeon KIM
1
;
See Won LEE
;
Lee Chun PARK
;
Jung Kwang SHIN
;
Nam Young PARK
;
Won MOON
;
Kyu Jong KIM
;
Moo In PARK
;
Seun Ja PARK
;
Hee Kyung CHANG
Author Information
1. Department of Internal Medicine, Kosin University Colledge of Medicine, Busan, Korea. parksj@ns.kosinmed.or.kr
- Publication Type:Original Article
- Keywords:
Gastric mucosal disease;
Forceps biopsy;
Endoscopic mucosal resection;
Histolgy
- MeSH:
Adenocarcinoma;
Adenoma;
Biopsy*;
Diagnosis;
Gastritis;
Humans;
Retrospective Studies;
Stomach Neoplasms;
Surgical Instruments*
- From:Korean Journal of Medicine
2006;71(6):600-608
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The correct histological diagnosis of a gastric adenoma is important, because an adenoma has been reported to be a precancerous lesion and is associated with focal gastric carcinoma. However, there is some discrepancy between the histology of a forceps biopsy and that of the endoscopic mucosal resection. This study compared the histological findings of a gastric mucosal lesion in the specimens of a forceps biopsy and an endoscopic mucosal resection. METHODS: 88 cases of gastric mucosal lesions, which had been removed by the endoscopic mucosal resection, were reviewed retrospectively. All the patients had undergone a forceps biopsy before the endoscopic mucosal resection. The histological findings of the specimens by a forceps biopsy were compared with those by resection. RESULTS: The histological findings were accordant at 52 of the 88 cases (59.1%). Among the 71 cases with adenoma or gastritis in the biopsied specimens, 13 cases (18.3%) were finally diagnosed with gastric cancer in the resected specimens. Among all the gastritis and adenomas determined by the forceps biopsy, the high-risk groups for adenocarcinomas were characterized by the following endoscopic findings: red-colored and depressed lesions. CONCLUSIONS: Biopsy specimens may not be representative of the entire lesion. Therefore, an endoscopic resection of a gastric mucosal lesion is needed for making an accurate histological diagnosis and treatment if adenomas such as red-colored or depressed lesions are suspected.
