Clinical Features of Menetrier's Disease in Korea.
- Author:
Yun Jeong LIM
1
;
Poong Lyul RHEE
;
Yung Ho KIM
;
Soon Jin LEE
;
Mi Sook LEE
;
Tae Wook KANG
;
Dong Il PARK
;
Jun Haeng LEE
;
Jae Kwon JANG
;
Hee Jung SON
;
Jae J KIM
;
Seung Woon PAIK
;
Jong Chul RHEE
;
Kyoo Wan CHOI
Author Information
1. Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sung Kyun Kwan University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Menetrier's disease;
Giant gastric fold;
Foveloar hyperplasia
- MeSH:
Dilatation;
Edema;
Female;
Gastritis, Hypertrophic*;
Hematemesis;
Hemorrhage;
Humans;
Hyperplasia;
Hypoalbuminemia;
Korea*;
Male;
Retrospective Studies;
Stomach
- From:Korean Journal of Gastrointestinal Endoscopy
2000;21(6):909-916
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Menetrier's disease is a poorly defined condition that is of unknown origin, characterized by giant folds in the stomach. The histologic features are foveolar hyperplasia and cystic dilatation of the gland. We presented the characteristic findings of Menetirer's disease in Korea with a review of literatures to understand the Menetirer's disease more precisely. METHODS: The sixteen cases of Menetrier's disease was reported in Korea. We analyzed their age, sex, symptoms, signs, laboratory findings and treatments, retrospectively. RESULTS: The average age was 46 years. There were 11 men and 4 women. The most common symptom was epigastric pain (94%). The most common sign were epigastric tenderness (69%) and pretibial pitting edema (63%). Patients were often associated with the hypoalbuminemia (73%). All patients showed hypertrophic folds on either gastrofiberscopy or upper gastrointestinal series. All patients showed foveolar hyperplasia histologically. Three patients were operated to control a massive upper gastrointesinal bleeding. Two patients were operated to control the intractable edema. Two patients were operated to exclude gastric malignancy. CONCLUSIONS: Menetrier's disease showed broad clinical features such as epigastric pain, hypoalbuminemia, massive hematemesis and mimicking gastric malignancy. The giant gastric folds and foveolar hyperplasia were the most commom and important findings in the Menetrier's disease.
