Case of Incidental Oncocytic Adrenocortical Neoplasm.
- Author:
Dong Hyun KIM
1
;
Ji Youn SUNG
;
Sang Youl RHEE
;
So Young PARK
;
Jung Il SON
;
Sang Ouk CHIN
;
Suk CHON
Author Information
1. Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea. bard95@hanmail.net
- Publication Type:Case Report
- Keywords:
Adrenocortical adenoma;
Oncocytoma;
Oxyphil cells
- MeSH:
Adenoma, Oxyphilic;
Adrenal Glands;
Adrenocortical Adenoma;
Cytoplasm;
Eosinophils;
Humans;
Oxyphil Cells
- From:Korean Journal of Medicine
2013;84(4):581-585
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Adrenal oncocytomas are very rare. Because most of them are benign and nonfunctioning, they are detected incidentally. Here, we report a case of nonfunctioning benign adrenocortical oncocytoma located in the left adrenal gland in a 54-year-old man who presented with no symptoms. The tumor was 4.5 x 3 x 3 cm in size and was predominantly composed of oncocytes, which exhibited abundant eosinophilic granular cytoplasm and were arranged with a nested or diffuse architecture without capsular or vascular invasion. Nuclear atypia and mitotic figures were not observed. A discussion of this case and a review of recent updates in the literature are presented. In patients with adrenocortical oncocytomas, treatment is similar to that for adrenocortical neoplasia. However, due to the risk of over-diagnosis of malignancy, and the better clinical outcomes associated with adrenocortical oncocytoma, more attention should be paid to the diagnosis of adrenocortical oncocytoma.