A Case of Dedifferentiated Chondrosarcoms: It was Changed From a Hamartoma.
10.4046/trd.2002.52.6.645
- Author:
Hak Ryul KIM
1
;
Sei Hoon YANG
;
Eun Taek JUNG
Author Information
1. Department of Internal Medicine, College of Medicine, Wonkwang University, Iksan, Korea. yshpul@wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
Dedifferentiated chondrosarcoms;
Hamartoma
- MeSH:
Biopsy, Needle;
Chondroma;
Chondrosarcoma;
Dyspnea;
Female;
Hamartoma*;
Humans;
Inflammation;
Middle Aged;
Pneumonectomy;
Sputum;
Thoracic Wall;
Thorax;
Tuberculosis, Pulmonary
- From:Tuberculosis and Respiratory Diseases
2002;52(6):645-650
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Extraosseous pulmonary chondrosarcoma is a rare neoplasm, which is characterized into two groups. One is termed a primary chondrosarcoma, and arise de novo (bronchial cartilage), the other is termed a secondary chondrosarcoma, and is superimposed on preexisting benign cartilagenous neoplasms, such as a chondroma or hamartoma. The preferred treatment is surgical resection. We recently experienced a secondary chondrosarcoma changed from a hamartoma.A 54-year-old woman was referred to our hospital becaused of an abnormal chest X-ray with mild dyspnea. We performed a percutaneous transthoracic needle biopsy and sputum examination. The abnormal mass had been diagnosed as a chondromatous hamortoma wit active pulmonary tuberculosis, which had been treated with anti-tuberculosis regimens. Despite her medication, and abnormal mass had grown. Therefore, we undertook a pneumonectomy with chest wall reconstruction.Histopathologically, the mass was grade II, dedifferenciated chondrosarcoma, with chronic granulomatous inflammation and necrosis.We suggest this case had changed from a chondromatous hamartoma to a dedifferentiated chondrosarcoma, with associated pulmonary tuberculosis. We report this case with a brief literature review.
