A Case of Subcutaneous Panniculitic T-cell Lymphoma.
- Author:
Sang Won KIM
1
;
Hyo Chan JANG
;
Dong Seok KIM
Author Information
1. Department of Dermatology, Catholic University of Taegu-Hyosung School of Medicine, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
Subcutaneous panniculitic;
T-cell lymphoma
- MeSH:
Adult;
Ankle;
Biopsy;
Dermis;
Female;
Herpesvirus 4, Human;
Humans;
Immunohistochemistry;
Leg;
Leprosy;
Leprosy, Lepromatous;
Lymphocytes;
Lymphoma, T-Cell*;
Skin;
T-Lymphocytes*
- From:Korean Journal of Dermatology
1999;37(8):1100-1103
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 41-year-old woman was presented with dusky-red colored, multiple subcutaneous infiltrative plaques of varing size(3-15cm in diameter) on both lower legs, the right ankle and the left antecubital area for about 6 months. Although she complained of sensory disturbance on the skin lesions which led to suspect lepromatous leprosy, there was no evidence of leprosy. Skin biopsy specimens showed dense small and medium-sized atypical lymphoid cell infiltrates in the subcutis, with a mixed septal and lobular pattern and a few scattered hemophagocytic cells. Angioinvasion and angiodestruction were seen in the focal area of deep dermis. Immunohistochemistry displayed positive reactions to LCA, CD3 and UCHL-1, but negative to CD20 and CD30. EBV antigen on the tissue was positive. The clinicopathologic features were consistent with subcutaneous panniculitic T-cell lymphoma.
