Prevalence and Risk Factors of Irritable Bowel Syndrome in Healthy Screenee Undergoing Colonoscopy and Laboratory Tests.
- Author:
Su Youn NAM
1
;
Byung Chang KIM
;
Kum Hei RYU
;
Bum Joon PARK
Author Information
1. Center for Cancer Prevention & Detection, National Cancer Center, Gyeonggi-do, Korea. mascha@ncc.re.kr
- Publication Type:Original Article
- Keywords:
Irritable bowel syndrome;
Colonoscopy;
Prevalence;
Risk factors
- MeSH:
Body Mass Index;
Colectomy;
Colonic Neoplasms;
Colonoscopy;
Drinking;
Female;
Humans;
Hypertension;
Hypnotics and Sedatives;
Inflammatory Bowel Diseases;
Irritable Bowel Syndrome;
Korea;
Logistic Models;
Mass Screening;
Odds Ratio;
Prevalence;
Surveys and Questionnaires;
Risk Factors;
Rome;
Smoke;
Smoking;
Stress, Psychological;
Thyroid Function Tests;
Weights and Measures
- From:Journal of Neurogastroenterology and Motility
2010;16(1):47-51
- CountryRepublic of Korea
- Language:English
-
Abstract:
INTRODUCTION: The prevalence of irritable bowel syndrome (IBS) after excluding organic disease has not been reported in Korea. METHODS: Of 5,605 participants in a health screening program, inclusion criteria were persons who underwent colonoscopy and completed questionnaires. Exclusion criteria were persons diagnosed with colon cancer, inflammatory bowel disease, previous colectomy, and abnormal results of thyroid function tests. IBS was defined by Rome III criteria. Physical and psychological stress was evaluated with visual analogue scales, ranging from 0 to 10. Risk factors for IBS were estimated with odds ratios (OR) and 95% confidence intervals (CI) using logistic regression analysis. RESULTS: The prevalence of IBS was 8.2% (5,605) in the total population and 9.1% (393/4,296) in the final study sample. IBS had a positive association with female sex (adjusted OR, 1.33; 95% CI, 1.00-1.79; p = 0.05) and current smoking (adjusted OR, 1.31; 95% CI, 1.00-1.71; p = 0.05). The prevalence of IBS increased with increased psychological stress (adjusted p for trend = 0.005) and decreased with increasing age (adjusted p for trend <0.001), with adjusted OR of 0.95 (95% CI, 0.68-1.33) for age of 40.0 to 49.9 years; 0.79 (95% CI, 0.54-1.15) for age of 50.0 to 59.9 years; and 0.51 (95% CI, 0.30-0.86) for age of 60 years or more, compared with age less than 40 years. Drinking status, body mass index, hypertension, diabetes, and use of sedatives had no association with IBS. CONCLUSIONS: The prevalence of IBS increased with decreasing age and increasing psychological stress, and was positively associated with female sex and current smoking.
