A Case of Pemphigoid Gestationis with Involvement of the Face.
- Author:
Jung Eun SEOL
1
;
Wonkyung LEE
;
Do Hyeong KIM
;
Se Won JUNG
;
Ho Suk SUNG
;
Hyojin KIM
Author Information
1. Department of Dermatology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea. derma09@hanmail.net
- Publication Type:Case Report
- Keywords:
Herpes gestationis;
Pemphigoid gestationis
- MeSH:
Adult;
Basement Membrane;
Blister;
Eosinophils;
Female;
Fluorescent Antibody Technique, Direct;
Humans;
Pemphigoid Gestationis*;
Pemphigoid, Bullous*;
Pregnancy;
Pregnancy Trimester, Third;
Pruritus
- From:Korean Journal of Dermatology
2015;53(10):802-805
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pemphigoid gestationis, also known as herpes gestationis, is a rare blistering disease associated with pregnancy, caused by autoantibody to the basement membrane component. It occurs in the second or third trimester of pregnancy or directly after delivery, as erythematous, urticarial papules, and plaques on the whole body, which aggravate to vesicles and bullae with severe pruritus. Histopathologically, subepidermal blisters and eosinophilic spongiosis are shown, and linear deposition of C3 in the dermoepidermal junction is seen on direct immunofluorescence assay. We present the case of 35-year-old woman who was diagnosed with pemphigoid gestationis, with the involvement of the uncommon site of the face.
