A Case of Neuromyelitis Optica(Devic's Disease).
- Author:
Chung Ryang CHA
1
;
Geum Gheal WHANG
;
Jong Soo LEE
;
Seung Jae LEE
;
Hyo Il PARK
Author Information
1. Department of Neurosurgery, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Neuromyelitis;
Optica Devic's disease;
Paraparesis bilateral optic neuritis
- MeSH:
Adrenocorticotropic Hormone;
Blood Sedimentation;
Cause of Death;
Child;
Diagnosis;
Humans;
Korea;
Lymphocytes;
Male;
Neuromyelitis Optica;
Optic Nerve;
Paraparesis;
Prognosis;
Respiratory Insufficiency;
Spinal Cord
- From:Journal of Korean Neurosurgical Society
1996;25(8):1723-1726
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
An 8 year-old boy was presented with typical symptoms of neuromyelitis optica. Hematologic data revealed leucocytosis and elevated erythrocyte sedimentation rate(ESR). CSF analysis showed elevated protein and lymphocyte dominant leucocytosis. Treatment with high dose steroid was administered. He recovered fully within a few weeks after the onset or paraparesis. Neuromyelitis optica is a clinical syndrome. Pathophysiologically, it is a autoimmune process involving the optic nerve and the spinal cord. It is characterized by rapid progressive paraparesis and bilateral visual disturbance. There are no definitive laboratory clues for diagnosis. Treatments including the use of steroid, ACTH, antiviral agent and immunosuppresant, all result in variable effect. Prognosis is very variable ranging from full recovery to death. The most common cause of death is respiratory failure with the cord lesions. Neuromyelitis optica is very rare in Korea. We report the case with review of the literature.
