Four Cases of Severe Fever with Thrombocytopenia Syndrome Occurring in Jeju.
- Author:
Sang Taek HEO
1
;
Minseok CHEON
;
Jae Wang KIM
Author Information
1. Department of Dermatology, Jeju National University School of Medicine, Jeju, Korea. rulid@jejunu.ac.kr
- Publication Type:Case Report
- Keywords:
Severe Fever with Thrombocytopenia Syndrome
- MeSH:
Bunyaviridae;
China;
Communicable Diseases, Emerging;
Diagnosis, Differential;
Diarrhea;
Far East;
Fever*;
Hemorrhagic Fever with Renal Syndrome;
Humans;
Korea;
Leptospirosis;
Leukopenia;
Phlebovirus;
Scrub Typhus;
Thrombocytopenia*;
Tick Bites;
Vomiting
- From:Korean Journal of Dermatology
2014;52(3):173-177
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel SFTS bunyavirus (SFTSV), a member of the genus Phlebovirus in the family Bunyaviridae. SFTSV is believed to be transmitted by Haemaphysalis longicornis. Common symptoms of SFTS include high fever, vomiting, diarrhea, thrombocytopenia, leukocytopenia, and multi-organ failure with an average case-fatality rate of 12~30%. In 2009, SFTS was firstly reported in China. In 2013, 27 cases of SFTS were documented in Korea, and 6 cases were confirmed on Jeju Island. Although the pathogenesis and transmission mode of SFTS remain unclear, SFTS is now considered endemic in East Asia. Accordingly, SFTS needs to be differentiated from scrub typhus, leptospirosis, and hemorrhagic fever with renal syndrome. We here report 4 cases of SFTS preceded by a tick bite, which were in need of a differential diagnosis of scrub typhus.
