The Change of the Serum Potassium K+ Level with the Use of Graft Preserved UW Solution or HTK Solution before and after Reperfusion in Liver Transplantation Recipients.
10.4097/kjae.2008.54.6.635
- Author:
Jeong Rim LEE
1
;
Kook Hyun LEE
;
Seng Sim BAE
;
Tae Kyong KIM
;
Choon gun RYU
Author Information
1. Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, Korea. manya1@hanmail.net
- Publication Type:Original Article
- Keywords:
liver transplantation;
potassium;
preservative solution;
reperfusion
- MeSH:
Adenosine;
Allopurinol;
Anesthesia;
Glucose;
Glutathione;
Humans;
Insulin;
Liver;
Liver Transplantation;
Mannitol;
Medical Records;
Organ Preservation Solutions;
Potassium;
Potassium Chloride;
Procaine;
Raffinose;
Reperfusion;
Retrospective Studies;
Transplants
- From:Korean Journal of Anesthesiology
2008;54(6):635-639
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: In liver transplantation, an increase of serum potassium [K+] after reperfusion is related to components of the preservation solution. However, the histidine-tryptophan-ketoglutarate (HTK) solution, which is now popularly used, has a twelve times lower [K+] as compared to the UW solution. This retrospective study was performed to compare the use of the UW solution with the HTK solution for changes in the serum [K+] during the early reperfusion period in liver transplantation recipients. METHODS: Anesthesia medical records of 366 liver transplant patients were reviewed and patients were enrolled in one of the two groups; recipients who received a transplanted liver preserved with the UW solution (UW group), and recipients received a liver preserved with the HTK solution (HTK group). Serum [K+] changes 5 min before, 5 min after, and 20 min after reperfusion for recipients in each group were compared. RESULTS: In the UW group, [K+] increased 5 min after reperfusion and decreased 20 min after reperfusion as compared to [K+] 5 min before reperfusion (3.93, 4.07, and 3.76 mM in 5 min before, 5 min after, and 20 min after reperfusion respectively; P < 0.001). In the HTK group, [K+] significantly decreased 5 min and 20 min after reperfusion as compared to [K+] 5 min before reperfusion (4.12, 3.79, and 3.75 mM; P < 0.001). CONCLUSIONS: When the HTK solution was used, the serum [K+] 5 min after reperfusion decreased as compared to the [K+] before reperfusion and didn't further decrease until 20 min after reperfusion.
