Factors associated with various clinical manifestations of Mycoplasma pneumonia in children.
10.4168/aard.2013.1.4.357
- Author:
Yoo Na KIM
1
;
Chul Hyue PARK
;
Su Hee KIM
;
Soo Jin YOO
;
Hyo Bin KIM
Author Information
1. Department of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, Korea. hbkim@paik.ac.kr
- Publication Type:Original Article
- Keywords:
Mycoplasma pneumonia;
Age factors;
Fever;
Pleural effusion;
Wheezing;
C-reactive protein
- MeSH:
Age Factors;
Agglutination Tests;
C-Reactive Protein;
Child*;
Child, Preschool;
Diagnosis;
Fever;
Humans;
Mycoplasma*;
Neutrophils;
Physical Examination;
Pleural Effusion;
Pneumonia;
Pneumonia, Mycoplasma*;
Prospective Studies;
Respiratory Sounds;
Risk Factors;
Thorax;
Young Adult
- From:Allergy, Asthma & Respiratory Disease
2013;1(4):357-361
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Mycoplasma pneumonia (MP) is a major cause of community-acquired pneumonia in children and young adults. We aimed to investigate the factors that may influence on the clinical manifestations of MP in children. METHODS: A total of 109 admitted children from October 2011 to February 2012 were prospectively enrolled with physical examination and laboratory tests (complete blood count, C-reactive protein [CRP], and particle agglutinin assay). The diagnosis of MP was made when there was an infiltration on the chest X-ray and the particle agglutination test was once over 1:640 or showed 4-fold increase in serial tests. They were grouped by age, fever duration after treatment, presence of pleural effusion and wheezing. RESULTS: Preschool children showed shorter duration of fever (P=0.001), more wheezing (P<0.001), lower segmented neutrophil (P<0.001), and lower CRP levels (P=0.004) compared to schoolchildren. Prolonged fever (>3 days) and pleural effusion were developed in children with higher CRP (P=0.018 and P=0.007). Wheezing has been developed in children with younger age (P=0.007). CONCLUSION: Younger age was a risk factor to develop wheezing in MP and prolonged fever and pleural effusion were more likely to develop in children with higher CRP.
