Biofilm-forming ability and adherence to poly-(methyl-methacrylate) acrylic resin materials of oral Candida albicans strains isolated from HIV positive subjects.
- Author:
Emel UZUNOGLU
1
;
Arzu Zeynep YILDIRIM BICER
;
Istar DOLAPCI
;
Arife DOGAN
Author Information
- Publication Type:In Vitro ; Original Article
- Keywords: PMMA; Candida albicans; Biofilms; Adhesion assay
- MeSH: Biofilms; Candida albicans*; Candida*; Gentian Violet; HIV*; Humans; Polymethyl Methacrylate; Prevalence; Stomatitis, Denture
- From:The Journal of Advanced Prosthodontics 2014;6(1):30-34
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: This study evaluated the adhesion to acrylic resin specimens and biofilm formation capability of Candida albicans strains isolated from HIV positive subjects' oral rinse solutions. MATERIALS AND METHODS: The material tested was a heat-cured acrylic resin (Acron Duo). Using the adhesion and crystal violet assays, 14 oral Candida albicans isolated from HIV-positive subjects and 2 references Candida strains (C. albicans ATCC 90028 and C. albicans ATCC 90128) were compared for their biofilm production and adhesion properties to acrylic surfaces in vitro. RESULTS: There were no significant differences in adhesion (P=.52) and biofilm formation assays (P=.42) by statistical analysis with Mann-Whitney test. CONCLUSION: Denture stomatitis and increased prevalence of candidal carriage in HIV infected patients is unlikely to be related to the biofilm formation and adhesion abilities of C. albicans to acrylic resin materials.