A Case Report of Long-Term Bisphosphonate Therapy and Atypical Stress Fracture of Bilateral Femur.
10.5535/arm.2013.37.3.430
- Author:
Yil Ryun JO
1
;
Hye Won KIM
;
Seock Ho MOON
;
Young Jin KO
Author Information
1. Department of Rehabilitation Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. yjko@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Osteoporosis;
Bisphosphonates;
Stress fracture
- MeSH:
Bone Resorption;
Diphosphonates;
Femur;
Fractures, Stress;
Hip Fractures;
Humans;
Osteoporosis
- From:Annals of Rehabilitation Medicine
2013;37(3):430-432
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bisphosphonates are potent inhibitors of bone resorption and considered as a gold standard and are generally recommended as first-line therapy in patients with osteoporosis. Though bisphosphonates are shown to significantly reduce the risk of vertebral, non-vertebral and hip fractures, recent reports suggest a possible correlation between long-term bisphosphonate therapy and the occurrence of insufficiency fractures owing to prolonged bone turnover suppression. We report a patient with non-traumatic stress fractures of bilateral femoral shafts related to long-term bisphosphonate therapy indicating the need for a critical evaluation of patients with long-term bisphosphonate therapy.
