Circulating Immune Complexes in Diabetics.
- Author:
Joo Young PARK
1
;
Sang Ae KIM
;
Se Jong KIM
;
Kap Bum HUH
;
Joo Deuk KIM
Author Information
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords: Circulating immune complexes; platelet aggregation test; diabetics
- MeSH: Antigen-Antibody Complex/metabolism*; Diabetes Mellitus/complications; Diabetes Mellitus/immunology*; Diabetes Mellitus, Insulin-Dependent/drug therapy; Diabetes Mellitus, Insulin-Dependent/immunology; Diabetes Mellitus, Non-Insulin-Dependent/immunology; Human; Insulin/therapeutic use; Platelet Aggregation; Time Factors
- From:Yonsei Medical Journal 1985;26(1):35-38
- CountryRepublic of Korea
- Language:English
- Abstract: Circulating immune complexes (ClC) were detected by platelet aggregation test (PAT) in 40.0% of 45 diabetics and by polyethylene glycol precipitation-complement consumption test (PEG-CC test) in 30.6% of 36 diabetics as compared to 5% and 10% of 20 normal control subjects for each test. The prevalence of CIC in diabetics was significantly higher than in the normal controls (P < 0.05%). There were no correlations between the presence of ClC detected by PAT and the duration of the disease, insulin treatment, or diabetic complications. Thus multiple factors must contribute to the increase of ClC in diabetics. The role of these various factors needs to be studied.
