Self-Expandable Polytetrafluoroethylene (PTFE)-covered Nitinol Stent for the Palliative Treatment of Malignant Biliary Obstruction.
10.3348/jkrs.2008.58.6.561
- Author:
Oong YOO
1
;
Gyoo Sik JUNG
;
Ji Ho KO
;
Byung Hoon HAN
;
Dong Hoon SHIN
Author Information
1. Department of Radiology, Gospel Hospital, College of Medicine, Kosin University, Korea. gsjung@medimail.co.kr
- Publication Type:Original Article
- Keywords:
Bile duct neoplasms;
Stents;
Radiology, interventional;
Polytetrafluoroethylene;
Cholestasis
- MeSH:
Alkaline Phosphatase;
Alloys;
Bile Duct Neoplasms;
Bilirubin;
Cholestasis;
Follow-Up Studies;
Humans;
Jaundice, Obstructive;
Palliative Care;
Pancreatitis;
Polytetrafluoroethylene;
Radiology, Interventional;
Stents;
Survival Rate
- From:Journal of the Korean Radiological Society
2008;58(6):561-569
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We wanted to determine the technical and clinical efficacy of placing a self-expandable PTFE-covered nitinol stent for the management of inoperable malignant biliary obstruction. MATERIALS AND METHODS: Thirty six patients with inoperable malignant biliary obstructions were treated by placement of self-expandable PTFE-covered nitinol stents (S & G Biotech Corporation, Seongnam, Korea). Clinical evaluation was done with assessment of the serum bilirubin and alkaline phosphatase levels, which were measured before and after stent placement within 1 week, at 1 month and at 3 months. The patient survival rate and stent patency rate were calculated with performing Kaplan-Meier survival analysis. RESULTS: Successful stent placement was achieved in all the patients without procedure-related complication. Pancreatitis as an early complication occurred in two cases. The serum bilirubin and alkaline phosphatase levels were significantly decreased after the procedure. During the follow-up, recurrent obstructive jaundice occurred in six cases; stent migration occurred in four cases and tumor overgrowth occurred in two cases. The survival rates were 97%, 80%, 67% and 59% at 1, 3, 6 and 9 months, respectively. The stent patency rates were 96%, 92%, 86% and 86% at 1, 3, 6 and 9 months, respectively. CONCLUSION: Self-expandable PTFE-covered nitinol stent placement seems to be technically feasible and effective for the palliative treatment of malignant biliary obstruction.
