Transient Left Ventricular Dysfunction After Percutaneous Patent Ductus Arteriosus Closure in Children.
10.4070/kcj.2008.38.11.596
- Author:
Yeo Hyang KIM
1
;
Hee Joung CHOI
;
Yongkeun CHO
;
Sang Bum LEE
;
Myung Chul HYUN
Author Information
1. Department of Pediatrics, School of Medicine, Keimyung University, Daegu, Korea.
- Publication Type:Original Article
- Keywords:
Ductus arteriosus, patent;
Catheter closure;
Ventricular dysfunction
- MeSH:
Cardiac Catheterization;
Cardiac Catheters;
Child;
Ductus Arteriosus, Patent;
Echocardiography, Doppler;
Follow-Up Studies;
Hemodynamics;
Humans;
Pulmonary Artery;
Sensitivity and Specificity;
Ventricular Dysfunction;
Ventricular Dysfunction, Left;
Ventricular Function
- From:Korean Circulation Journal
2008;38(11):596-600
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: The goal of this study was to assess changes in left ventricular (LV) function and to identify pre-closure factors associated with LV dysfunction {fractional shortening (FS) below 29%} after transcatheter patent ductus arteriosus (PDA) closure. SUBJECTS AND METHODS: Forty-three pediatric patients with PDAs underwent cardiac catheterization for hemodynamic studies and intervention. Doppler echocardiography was performed at pre-closure, post-closure, and follow-up. RESULTS: S' and A' of the septum and mitral annulus were significantly decreased at post-closure and follow-up, respectively. In five of eight patients with Qp/Qs ratios over 1.60 and Pp/Ps ratios over 0.32 at pre-closure, the FS was decreased below 29% at post-closure. Qp/Qs ratio over 1.60 and Pp/Ps ratio over 0.32 at pre-closure had a sensitivity of 86% and a specificity of 84% for predicting FS to be below 29% at post-closure. CONCLUSION: Larger amounts of pre-closure left-to-right shunting and higher pulmonary artery pressure were associated with an increased likelihood of FS <29% after closure. The results of this study suggest that serial assessments of ventricular function are needed after PDA occlusion in patients with high Qp/Qs and Pp/Ps ratios.
