Endoscopic Submucosal Dissection for Early Gastric Cancer and Gastric Adenoma.
- Author:
Jin Seok JANG
1
;
Eun Joo LEE
;
Sung Wook LEE
;
Jong Hun LEE
;
Myung Hwan ROH
;
Sang Young HAN
;
Seok Reyol CHOI
;
Jin Sook JEONG
Author Information
1. Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea. sychoi@dau.ac.kr
- Publication Type:Original Article ; English Abstract
- Keywords:
Endoscopic submucosal dissection;
Early gastric cancer;
Adenoma
- MeSH:
Adenoma/pathology/*surgery;
Adult;
Aged;
Dissection/instrumentation;
Female;
Gastric Mucosa/pathology/*surgery;
*Gastroscopy;
Humans;
Male;
Middle Aged;
Neoplasm Staging;
Retrospective Studies;
Stomach Neoplasms/pathology/*surgery;
Surgical Procedures, Minimally Invasive
- From:The Korean Journal of Gastroenterology
2007;49(6):356-363
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Endoscopic Submucosal Dissection (ESD) is a new endoscopic mucosal resection (EMR) technique which enables en bloc resection even in large and depressed lesions. The aims of this study were to assess the therapeutic efficacy and the safety of ESD in gastric adenoma and in early gastric cancer (EGC). METHODS: We analyzed 101 lesions in 101 patients. ESD with insulated-tipped (IT) knife were performed in 52 adenomas and 49 EGCs from January 2003 to December 2005 in Dong-A University Hospital. RESULTS: The mean size of the lesion was 2.58 cm (0.7-4.5 cm). En bloc resection rate was 90.1% which was influenced by size (p>0.05). Complete resection rate was 83.2% even in large or in malignant tumors (p>0.05). Bleeding after ESD occurred in 41.6%. Tumor recurrence rate was 2.0%. CONCLUSIONS: ESD with IT knife is effective for the treatment of EGC and gastric adenoma even in large or in malignant lesions without definite increased risk of complications.
