BRCA1-mutated ovarian cancer with skin metastasis: a case report.
10.5468/ogs.2017.60.5.477
- Author:
So Ra OH
1
;
Jung Woo PARK
;
Hyun Young KWON
;
Seo Hee RHA
Author Information
1. Department of Obstetrics and Gynecology, Dong-A University College of Medicine, Busan, Korea. mdpjw1216@gmail.com
- Publication Type:Case Report
- Keywords:
Skin metastases;
Ovarian neoplasms;
BRCA mutation
- MeSH:
DNA Mismatch Repair;
Humans;
Middle Aged;
Neoplasm Metastasis*;
Ovarian Neoplasms*;
Prognosis;
Risk Factors;
Skin*
- From:Obstetrics & Gynecology Science
2017;60(5):477-480
- CountryRepublic of Korea
- Language:English
-
Abstract:
The major risk factor for ovarian cancer (OC) is mutation of the BRCA1 or BRCA2 DNA mismatch repair genes, which occurs in approximately 10% of OC cases. Most previous studies have demonstrated that BRCA1- and BRCA2-mutated OCs are associated with better prognosis than sporadic OCs. However, information about the patterns and clinical course of the metastatic spread of BRCA-mutated OCs is limited. Herein, we describe a case of OC with a BRCA1 mutation and skin metastases in a 49-year-old patient, which to the best of our knowledge has not been reported previously.
