Dysfunction of the Prosthetic Aortic Valve in Idiopathic Hypereosinophilic Syndrome: A case report.
- Author:
Chong Bin PARK
1
;
Dong Gon YOO
;
Kyu Wan SUNG
;
Sang Sig JUNG
;
Gil Hyun KANG
;
Chong Wook KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Gangneung Asan Hospital, Korea. jvin@gnah.co.kr
- Publication Type:Case Report
- Keywords:
Hypereosinophilic syndrome, idiopathic;
Aortic valve, surgery
- MeSH:
Aortic Valve*;
Cardiomyopathy, Restrictive;
Female;
Fibrosis;
Heart;
Humans;
Hydroxyurea;
Hypereosinophilic Syndrome*;
Male;
Middle Aged;
Multiple Organ Failure;
Thrombosis
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2007;40(4):297-300
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Idiopathic hypereosinophilic syndrome is a rare systemic, leukoproliferative disorder characterized by eosinophil- mediated tissue injury causing multiple organ failure, including the heart. Cardiac involvement occurs in more than 75% of patients with hypereosinophilic syndrome. Cardiac manifestations include subendocardial fibrosis, thrombus leading to peripheral emboli, restrictive cardiomyopathy, and valvular dysfunction. It is more common in men than in women (9:1), and trends to present between the ages of 20 and 50 years. Presentation in childhood is unusual. We report for the first time a case of a 58-year-old man with idiopathic hypereosinophilic syndrome manifested by prosthetic aortic valve dysfunction that was successfully treated by steroid and hydroxyurea therapy after surgical valvular replacement.
