Restoration of Blood Pressure after Administering Methylene Blue for Vasoplegic Syndrome, which Developed after Open Heart Surgery for Septic Infective Endocarditis: A case report.
- Author:
Sak LEE
1
;
Mi Kyung BAE
;
Gi Jong YI
;
Young Nam YOUN
;
Suk Won SONG
;
Do Kyun KIM
Author Information
1. Department of Thoracic and Cardiovascualr Surgery, Severance Hospital, Yonsei University College of Medicine, Korea. dkkim0327@hanmail.net
- Publication Type:Case Report
- Keywords:
Cardiopulmonary bypass;
Methylene blue;
Vasoplegic syndrome
- MeSH:
Blood Pressure*;
Cardiopulmonary Bypass;
Endocarditis*;
Guanylate Cyclase;
Heart*;
Humans;
Methylene Blue*;
Mortality;
Nitric Oxide;
Thoracic Surgery*;
Vasoplegia*
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2007;40(4):305-308
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Vasoplegic syndrome occurs in 8~10% of patients following cardiac surgery, and this happens in part because of inducing the inflammatory response. Nitric oxide and guanylate cyclase play an important role in this response, and this is associated with increased morbidity and mortality. For our case, we administered methylene blue (MB), an inhibitor of guanylate cyclase, early after performing cardiopulmonary bypass in a patient with vasoplegic syndrome. The patient recovered immediately after MB administration and maintained an optimal blood pressure without the aid help of any vasopressors.
