Study on bisphosphonate-related osteonecrosis of the jaw (BRONJ): case report and literature review.
10.5125/jkaoms.2010.36.4.291
- Author:
Yeo Gab KIM
1
;
Baek Soo LEE
;
Yong Dae KWON
;
Joon Ho SUH
;
Sang Mi JEEN
Author Information
1. Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyung Hee University, Seoul, Korea. kyukab@khu.ac.kr
- Publication Type:Case Report
- Keywords:
Bisphosphonate;
Osteonecrosis;
Osteoporosis;
Jaw diseases
- MeSH:
Bisphosphonate-Associated Osteonecrosis of the Jaw;
Breast Neoplasms;
Diphosphonates;
Jaw Diseases;
Neoplasm Metastasis;
Osteonecrosis;
Osteoporosis;
Prescriptions;
Prostatic Neoplasms
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2010;36(4):291-302
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a side effect of Bisphosphonates (BPs) use. These days, oral bisphosphonates are normally prescribed to treat osteoporosis. Intravenous BPs are used extensively to treat osteolytic bone lesions related to multiplemyeloma and bone metastasis of solid cancers, breast cancer or prostate cancer. As the prescription of BPs is universalized and the number of people treated with BPs is increasing, an accurate understanding and proper management of BRONJ are required. The aim of this study was to improve the clinicians'understanding of BRONJ by reviewing the literature. To achieve this, this paper introduces case reports as well as the current concept of BRONJ based on the 2009 updates by American Association of Oral and Maxillofacial (AAOMS) including the definition, epidemiology, etiology, diagnosis, treatment and prevention of BRONJ.
