Squamous cell carcinoma arising within a maxillary odontogenic keratocyst: A rare occurrence.
10.5624/isd.2017.47.2.135
- Author:
Elnaz JALALI
1
;
Elie M FERNEINI
;
Kandasamy RENGASAMY
;
Aditya TADINADA
Author Information
1. Eliray Oral and Maxillofacial Radiology Consulting Services, Miami, FL, USA.
- Publication Type:Case Report
- Keywords:
Carcinoma, Squamous Cell;
Odontogenic Cysts;
Maxilla;
Cell Transformation, Neoplastic
- MeSH:
Biopsy;
Carcinoma, Squamous Cell*;
Cell Transformation, Neoplastic;
Epithelial Cells*;
Humans;
Maxilla;
Odontogenic Cysts*
- From:Imaging Science in Dentistry
2017;47(2):135-140
- CountryRepublic of Korea
- Language:English
-
Abstract:
Squamous cell carcinoma (SCC) arising within the lining of an odontogenic keratocyst (OKC) is a rare occurrence. Although potentially locally destructive, OKC is a benign odontogenic process that typically presents with clinical and radiographic features characteristic of a benign intraosseous neoplasm. We present the clinical and radiographic features of a maxillary mass that demonstrated SCC arising from the lining of an OKC. Although the initial clinical and radiographic presentation suggested an infection or malignant neoplasm, biopsies revealed an infiltrative well-differentiated SCC contiguous with and arising from the focus of a pre-existing OKC. The patient subsequently underwent a type II hemi-maxillectomy with neoadjuvant chemoradiation. This report discusses the clinical and radiographic features associated with intraosseous malignancies, especially those arising from an otherwise benign odontogenic lesion. While the majority of OKCs are benign, the current report illustrates the potential for carcinomatous transformation within the lining of an OKC.
