Evaluation of the HM-JACK Automatic Analyzer for Fecal Occult Blood Test.
- Author:
Seung Bok HONG
1
;
Hyun Soo KIM
;
Hyo Soon PARK
;
Do Hoon LEE
Author Information
1. Department of Laboratory Medicine, Pundang Jesaeng General Hospital, Sungnam, Korea. dhlee@dmc.or.kr
- Publication Type:Original Article
- Keywords:
Fecal occult blood test;
Colorectal cancer;
HM-JACK;
OC-Hemodia
- MeSH:
Agglutination;
Colorectal Neoplasms;
Latex;
Mass Screening;
Occult Blood*
- From:Journal of Laboratory Medicine and Quality Assurance
2002;24(2):221-224
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Fecal occult blood test is a useful method for mass screening of colorectal cancer. HM-JACK is automatic analyzer for detecting fecal occult blood with latex agglutination methods. We evaluated its apparatus for compatibility for clinical testing. METHODS: The linearity, precision and effect of temperature and container in stool storage were evaluated. The comparison study with OC-Hemodia and prozone phenomenon were evaluated. RESULTS: The linearity was good(R(2)=0.997) and coeffiecinet variation(CV) of within-day precision were 4.6% and 2.6% in low concentration and high concentration. The CV of between-day precision were 4.8% and 3.5%. The hemoglobin concentration of 0.1 g/dL(1x10(6) ng/mL) was measured to 651 ng/mL for Antigen excess zone. The hemoglobin were more decreased in room temperature storage and usual container storage than in low temperature storage and HM-JACK container storage. The concordance rate between HM-JACK and OC-Hemodia was 90%. CONCLUSION: HM-JACK showed good performance for linearity, precision and comparison study. Therefore, it can be used effectively in clinical laboratory due to convenience, and possibility of quantitation and fast reporting.
