Frozen Section Diagnosis of Breast Lesions.
- Author:
Hyung Jin KIM
1
;
Woo Chan PARK
;
Gyeongsin PARK
;
Sang Seol JUNG
Author Information
1. Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. hj@cmc.md
- Publication Type:Original Article
- Keywords:
Breast;
Frozen section;
Breast cancer
- MeSH:
Breast Neoplasms;
Breast*;
Diagnosis*;
Frozen Sections*;
Paraffin;
Retrospective Studies;
Selection Bias;
Sensitivity and Specificity
- From:Journal of the Korean Surgical Society
2002;63(6):445-448
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Frozen sections of breast specimens can be used to determine malignancy in a suspected lesion of the breast during operation. However, this procedure always has a potential risk of reporting a false positive or negative. This study was performed to evaluate the accuracy of the frozen section diagnosis of breast lesions. METHODS: A retrospective study to comparing the results of frozen and paraffin, section diagnosis was undertaken. RESULTS: 178 frozen breast section diagnoses were made between January 1995 and December 1996 at Kangnam St. Mary hospital. There were no false positive reports (0%) but 3 false negative reports (1.7%). The causes of a false negative were sampling error in 2 cases and interpretation error in the other. The sensitivity and specificity of the frozen section diagnosis were 94.5 and 99.2%, respectively. CONCLUSION: Despite the high sensitivity and specificity of the breast specimen frozen section diagnosis, care should be taken when making a decision on the frozen section diagnosis due to the possibility of false negative results.
