Relationship between Intussusception and Vitamin C Concentrations of Whole Blood and Plasma.
- Author:
Ji Hyoun SEO
1
;
Jeum Su KIM
;
Ji Young HWANG
;
Jin Su JUN
;
Ji Hoe PARK
;
Eun A KIM
;
Jae Young LIM
;
Myoung Bum CHOI
;
Chan Hoo PARK
;
Hyang Ok WOO
;
Hee Shang YOUN
Author Information
1. Department of Pediatrics, College of Medicine, Gyeongsang National University, Jinju, Korea. hsyoun@nongae.gsnu.ac.kr
- Publication Type:Original Article
- Keywords:
Intussusception;
Vitamin C
- MeSH:
Adenoviridae;
Adenoviridae Infections;
Ascorbic Acid*;
Child;
Fever;
Gastrointestinal Hemorrhage;
Human Body;
Humans;
Ileum;
Intussusception*;
Leukocytosis;
Lymph Nodes;
Peyer's Patches;
Plasma*;
Vitamins*
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
2001;4(2):167-174
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Adenovirus infection with swollen Peyer patches in the ileum, known as one of the causes of intussusception, may cause vitamin C depletion in human body because vitamin C is a first line antioxidant. Or low vitamin C status in human body makes the man more susceptible to infection of adenovirus in the ileum with a markedly swollen lymph node. In this study, we tried to find out the relationship between pediatric intussusceptions and vitamin C concentrations of whole blood and plasma. METHODS: Whole blood and plasma vitamin C concentrations of fifty-seven patients with intussusceptions from May 1995 to December 1998 at the Gyeongsang National University Hospital were compared with those of 256 normal healthy children. Vitamin C was measured by the 2,4-dinitrophenylhydrazine methods. RESULTS: The average age of patients (male=39, female=18) with intussusceptions was fifteen months of age. Whole blood vitamin C concentrations of patients and healthy children were 1.49+/-0.64 mg/dL, and 2.18+/-0.49 mg/dL, respectively. Plasma vitamin C concentrations of patients and healthy children were 0.59+/-0.36 mg/dL, 1.47+/-0.56 mg/dL, respectively. But no differences in the vitamin C concentrations of whole blood and plasma according to age, degree of leukocytosis, fever, interval from onset, hematochezia, and need for operation were found. CONCLUSION: Whole blood and plasma vitamin C concentrations of patients with intussusceptions were lower than those of healthy children (P=0.0001). Prospective studies are needed to elucidate whether these results were consequences or causes of intussusceptions.
