Postictal Serum Prolactin Values and Its Significance in Convulsive Disorder.
- Author:
Wan Yong SHIN
;
Sa Jun CHUNG
;
Chang Il AHN
- Publication Type:Original Article
- MeSH:
Biomarkers;
Child;
Humans;
Hyperprolactinemia;
Prolactin*;
Radioimmunoassay;
Seizures
- From:Journal of the Korean Pediatric Society
1994;37(11):1573-1578
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The authors analysed 196 cases of convulsive disorder in children who were admitted to the pediatric department of Kyunghee Hospital from June 1993. Blood samples were drawn immediately following seizures on arrival. Serum prolactin values were measured by radioimmunoassay. The results obtained were as follows: 1) Mean serum prolactin value was 55.4+/-20.8ng/ml in generalized seizures within 1 hr following seizures, 22.5+/-3.9ng/ml in partial seizures. There was a significant difference between generalized scizures and partial scizures (p<0.05). 2) Mean serum prolactin value was 23.5+/-9.7ng/ml in generalized seizures within 1~3 hrs following seizures, 10.4+/-4.9ng/ml in partial seizures. There was a significant difference between generalized seizures and partial seizures (p<0.05). 3) Mean serum prolactin value was 9.5+/-4.4ng/ml in generalized seizures 3 hrs following seizures, 9.8+/-4.8ng/ml in partial seizures. There was no significant difference between generalized seizures and partial seizures (p>0.05). We found transient hyperprolactinemia following generalized seizures but a little change following gartial seizures. Postictal elevation of serum prolactin may represent a biochemical marker of generalized and partial seizures.
