Differentiation of Deep Subcortical Infarction Using High-Resolution Vessel Wall MR Imaging of Middle Cerebral Artery.
10.3348/kjr.2017.18.6.964
- Author:
Yun Jung BAE
1
;
Byung Se CHOI
;
Cheolkyu JUNG
;
Yeon Hong YOON
;
Leonard SUNWOO
;
Hee Joon BAE
;
Jae Hyoung KIM
Author Information
1. Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Korea. byungse.choi@gmail.com
- Publication Type:Original Article
- Keywords:
Middle cerebral artery;
Cerebral infarction;
Stroke;
Magnetic Resonance imaging;
Plaque;
Atherosclerotic;
Highresolution vessel wall imaging
- MeSH:
Cerebral Infarction*;
Constriction, Pathologic;
Ethics Committees, Research;
Humans;
Infarction;
Informed Consent;
Magnetic Resonance Imaging*;
Middle Cerebral Artery*;
Retrospective Studies;
Stroke
- From:Korean Journal of Radiology
2017;18(6):964-972
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To evaluate the utility of high-resolution vessel wall imaging (HR-VWI) of middle cerebral artery (MCA), and to compare HR-VWI findings between striatocapsular infarction (SC-I) and lenticulostriate infarction (LS-I). MATERIALS AND METHODS: This retrospective study was approved by the Institutional Review Board, and informed consent was waived. From July 2009 to February 2012, 145 consecutive patients with deep subcortical infarctions (SC-I, n = 81; LS-I, n = 64) who underwent HR-VWI were included in this study. The degree of MCA stenosis and the characteristics of MCA plaque (presence, eccentricity, location, extent, T2-high signal intensity [T2-HSI], and plaque enhancement) were analyzed, and compared between SC-I and LS-I, using Fisher's exact test. RESULTS: Stenosis was more severe in SC-I than in LS-I (p = 0.040). MCA plaque was more frequent in SC-I than in LS-I (p = 0.028), having larger plaque extent (p = 0.001), more T2-HSI (p = 0.001), and more plaque enhancement (p = 0.002). The eccentricity and location of the plaque showed no significant difference between the two groups. CONCLUSION: Both SC-I and LS-I have similar HR-VWI findings of the MCA plaque, but SC-I had more frequent, larger plaques with greater T2-HSI and enhancement. This suggests that HR-VWI may have a promising role in assisting the differentiation of underlying pathophysiological mechanism between SC-I and LS-I.
