Gemcitabine-Induced Radiation Recall Dermato-Myositis.
10.4046/trd.2006.61.2.167
- Author:
Hee Sun NO
1
;
Hee Hwan LIM
;
Jung Hoon KIM
;
Jang Hyun CHO
;
Jeong Kwon HUH
;
Sung In CHO
;
Ji Young YOO
;
Cheol Hyeon KIM
;
Jae Cheol LEE
Author Information
1. Department of Internal Medicine, Korea Cancer Center Hospital, Seoul, Korea. jclee@kcch.re.kr
- Publication Type:Case Report
- Keywords:
Radiation recall;
Gemcitabine;
Lung cancer
- MeSH:
Carcinoma, Non-Small-Cell Lung;
Drug Therapy;
Erythema;
Female;
Femur;
Humans;
Lung Neoplasms;
Radiodermatitis;
Skin;
Thigh
- From:Tuberculosis and Respiratory Diseases
2006;61(2):167-170
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A radiation recall reaction refers to an inflammatory reaction at previous irradiated areas subsequent to the administration of a variety of pharmacological agents. The skin is the major site of radiation recall reactons with the muscle and internal organs being less commonly affected. These reactions usually occur days to weeks after exposure to the causative agents. We report a case of gemcitabine-induced radiation recall dermato-myositis the developed in a female patient with a metastatic non-small cell lung cancer. She had received a palliative radiation therapy of 3900 cGy to the metastatic lesion on the femur shaft prior to chemotherapy. The pain, swelling and erythema of the left thigh resolved after the cessation of gemcitabine and the use of a systemic steroid.
