Clinicopathologic and immunophenotypic study of non-Hodgkin's lymphoma in Korea.
10.3346/jkms.1992.7.3.193
- Author:
Chul Woo KIM
1
;
In Sun KIM
;
Young Haeh KO
;
Hye Je CHO
;
Woo Ick YANG
;
Geon Young KWON
;
Dong Geun LEE
;
Hyung Bae MOON
;
Chae Hong SUH
;
Sang Woo JUHNG
;
Jung Dal LEE
;
Sang Ho KIM
Author Information
1. Department of Pathology, Seoul National University College of Medicine, Yongon-Dong, Chongno-Ku, Korea.
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Malignant lymphoma;
Korean;
Classification;
Immunophenotype;
Non-Hodgkin's lymphoma
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Child;
Female;
Humans;
Immunophenotyping;
Korea;
Lymphoma, Non-Hodgkin/classification/*immunology/*pathology;
Male;
Middle Aged
- From:Journal of Korean Medical Science
1992;7(3):193-198
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study sponsored by the Lymphoreticular Study Group of the Korean Society of Pathologists was carried out to provide nationwide data about the histopathologic-immunophenotypic features of malignant lymphomas in Korea. Two hundred and ninety Non-Hodgkin's lymphoma (NHL) among 312 malignant lymphomas collected from three representative areas in Korea were histologically reclassified. Two hundred and fifty three cases were immunohistochemically studied. T-cell lymphoma comprised 35.2% of NHL in this study and showed a quite comparable incidence to that of Japan and China, but it was much higher than in Western countries. A very low prevalence rate of the follicular variety (4.0%) and a higher propensity of primary extranodal involvement (60%) are additional characteristics of NHL in Korea. The most common histologic subtype of B cell lymphoma was diffuse large cell type, whereas the most common subtype of T cell lymphoma was diffuse mixed small and large cell type.