Spinal epidural granulocytic sarcoma preceding acute myelogenous leukemia.
10.3346/jkms.1992.7.3.291
- Author:
Hoon KOOK
1
;
Tai Ju HWANG
;
Kyoung CHOE
;
Dong Wook YANG
;
Jong Hee NAM
;
Chang Soo PARK
Author Information
1. Department of Pediatrics, Chonnam University Medical School, Kwangju, Korea.
- Publication Type:Case Reports
- Keywords:
Granulocytic sarcoma;
Spinal epidural;
Aleukemic patient
- MeSH:
Child;
Epidural Neoplasms/*complications/pathology;
Humans;
Immunoenzyme Techniques;
Leukemia, Myeloid/*complications/pathology;
Leukemia, Myeloid, Acute/*complications/pathology;
Male;
Neoplasms, Second Primary
- From:Journal of Korean Medical Science
1992;7(3):291-296
- CountryRepublic of Korea
- Language:English
-
Abstract:
A rare case of spinal epidural granulocytic sarcoma (GS) preceding acute myelogenous leukemia is described. A 10-year-old boy presented with lower leg weakness. The initial diagnosis was a histiocytic lymphoma, and he was treated accordingly. No evidence of bone marrow involvement was found at that time. The correct diagnosis of epidural GS was made possible in retrospect by using immunoperoxidase staining for lysozyme fourteen months later when the patient showed the full-blown features of leukemia. This rare tumor should be considered in the differential diagnosis of an epidural mass with cord compression in patients with or even without acute leukemia, because early diagnosis followed by appropriate combined chemotherapy and radiation may obviate surgical intervention and eventually prevent leukemic transformation.
