The Clinical Characteristics and Prognosis after Acute Ingestion of Glacial Acetic Acid.
- Author:
Gab Yong CHOI
1
;
Young Gi MIN
;
Yoon Seok JUNG
;
Joon Pil CHO
;
Sang Cheon CHOI
Author Information
1. Emergency Department, Ajou University School of Medicine, Suwon, Korea. avenue59@ajou.ac.kr
- Publication Type:Original Article
- Keywords:
Glacial acetic acid;
Poisoning;
Caustics
- MeSH:
Acetic Acid;
Acidosis;
Caustics;
Eating;
Emergencies;
Humans;
Hypotension;
Intensive Care Units;
Intubation, Intratracheal;
Liver Failure;
Medical Records;
Multiple Organ Failure;
Oliguria;
Oral Ulcer;
Prognosis;
Retrospective Studies
- From:Journal of The Korean Society of Clinical Toxicology
2012;10(2):91-96
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: A retrospective study with a literature review was conducted to identify the clinical characteristics and prognosis after the acute ingestion of glacial acetic acid. METHODS: The medical records of 20 patients,who had presented to the emergency department of Ajou University Hospital complaining of the acute ingestion of glacial acetic acid between January 2006 and December 2011, were examined retrospectively. RESULTS: Among the 172 patients admitted for caustics injury, 20 patients ingested glacial acetic acid. The mean age of the patients was 55+/-23.5, and the mean volume of the acid was 84.5+/-71.3 ml. The clinical features included 1) oral ulcers in 12 patients (63.2%), 2) respiratory difficulties in 11 patients (57.9%), 3) oliguria in 8 patients (42.1%), 4) renal toxicity in 7 patients (36.8%), 5) hepatic failure in 7 patients (36.8%), 6) disseminated intravascular boagulopathyin 7 patients (36.8%), 7) low blood pressure in 8 patients (42.1%), and 8) mental changes in 9 patients (47.4%). Ten patients required endotracheal intubation. Nine patients were admitted to the intensive care unit, and 5 patients expired. CONCLUSION: The ingestion of glacial acetic acid can cause severe symptoms, such as metabolic acidosis, multiple organ failure and upper airway swelling frequently and has a high mortality rate. Therefore, aggressive treatment, including endotracheal intubation, should be considered at the early stages.
