Erectile Response to Intracavernous Injection of Prostaglandin E1 or Papaverine in Impotence Patients with Diabetes Mellitus.
- Author:
Wall Bum KIM
1
;
Kyung Kun SEO
;
Sae Chul KIM
Author Information
1. Chung-Ang University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
prostaglandin E1;
papaverine;
erectile response
- MeSH:
Alprostadil*;
Diabetes Mellitus*;
Erectile Dysfunction*;
Humans;
Male;
Papaverine*
- From:Korean Journal of Urology
1997;38(4):422-426
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To assess the erectile response to intracavernous injection of prostaglandin E1 (PGE 1) or papaverine in the impotence patients with diabetes mellitus (DM), and to determine the factors which would predict good response to either drug. MATERIALS AND METHODS: We injected papaverine (10~60 mg) or PGE1 (10~20 mg) into cavernosal tissues of 305 impotence patients with DM (mean age; 56.1 years). Erectile response was classified into poor, moderate, or good, and was comparatively analyzed according to kinds of vasoactive agents, patients` age, duration of DM and impotence, and treatment modality of DM. RESULTS: The frequency of good response to PGE1 was significantly higher than to papaverine (61.5% vs. 42.8%; p<0.05). However, no association between erectile response and patients` age, duration of impotence and DM, and treatment modality of DM was noted. CONCLUSIONS: Prostaglandin E1 seems to be more effective substance than papaverine for intracavernous injection therapy in impotence patients with DM.
