Guillain-Barre Syndrome With Antibody to Ganglioside GT1a.
- Author:
Tae Il YANG
1
;
Young Eun PARK
;
Jong Kuk KIM
;
Seong Yi CHA
;
Tae Hyoung KIM
;
Dae Seong KIM
Author Information
1. Department of Neurology, Pusan National University School of Medicine, Busan, Korea. yeun0407@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Guillain-Barre syndrome;
Oropharyngeal palsy;
Anti-GT1a IgG
- MeSH:
Antibodies;
Deglutition Disorders;
Dyspnea;
Gangliosides;
Guillain-Barre Syndrome;
Humans;
Immunoglobulin G;
Paralysis;
Phenotype;
Quadriplegia
- From:Journal of the Korean Neurological Association
2010;28(4):291-294
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The presence of serum antibodies to various gangliosides, such as anti-GQ1b, is closely related to the clinical features of Guillain-Barre syndrome. However, the phenotype associated with anti-GT1a IgG has not yet been determined, although it has been detected in some cases of the pharyngeal-cervical-brachial variant. We report herein two patients harboring anti-GT1a IgG who both presented with profound dyspnea, dysphagia, and quadriparesis. The findings of this report suggest that the anti-GT1a antibody specifies a clinical feature of oropharyngeal palsy.
