Bilateral Optic Neuritis as the First Manifestation of Systemic Lupus Erythematosus Associated With Neuromyelitis Optica.
- Author:
Young NOH
1
;
Eun Ha KANG
;
Jeong Min HWANG
;
Ji Soo KIM
Author Information
1. Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea. jisookim@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Optic neuritis;
Systemic lupus erythematosus;
Neuromyelitis optica
- MeSH:
Adult;
Central Nervous System;
Demyelinating Diseases;
Female;
Humans;
Immunoglobulin G;
Lupus Erythematosus, Systemic;
Myelitis, Transverse;
Neuromyelitis Optica;
Optic Neuritis
- From:Journal of the Korean Neurological Association
2010;28(4):323-325
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neuromyelitis optica (NMO) is a demyelinating disease of the central nervous system that is characterized by severe episodes of transverse myelitis and optic neuritis. Aquaporin-4-specific autoantibody (NMO IgG) is the marker of NMO. We report herein a 28-year-old woman with systemic lupus erythematosus (SLE) that manifested with bilateral optic neuritis. She had NMO IgG in addition to clinical and serologic characteristics of SLE. This is the first report of a patient with SLE and NMO IgG that manifested with sequential bilateral optic neuritis.