Long-term Mortality in Adult Orthotopic Heart Transplant Recipients.
10.3346/jkms.2011.26.5.599
- Author:
Sung Ho JUNG
1
;
Jae Joong KIM
;
Suk Jung CHOO
;
Tae Jin YUN
;
Cheol Hyun CHUNG
;
Jae Won LEE
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. jwlee@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Transplantation;
Heart;
Death
- MeSH:
Adult;
Anastomosis, Surgical/methods;
Female;
Follow-Up Studies;
Graft Rejection/mortality;
Heart Transplantation/*mortality;
Humans;
Immunosuppression/methods;
Infection/mortality;
Male;
Middle Aged;
Neoplasms/mortality;
Postoperative Complications/mortality/surgery;
Survival Rate;
Transplantation/*mortality;
Treatment Outcome
- From:Journal of Korean Medical Science
2011;26(5):599-603
- CountryRepublic of Korea
- Language:English
-
Abstract:
Heart transplantation is now regarded as the treatment of choice for end-stage heart failure. To improve long-term results of the heart transplantation, we analyzed causes of death relative to time after transplantation. A total of 201 consecutive patients, 154 (76.6%) males, aged > or = 17 yr underwent heart transplantation between November 1992 and December 2008. Mean ages of recipients and donors were 42.8 +/- 12.4 and 29.8 +/- 9.6 yr, respectively. The bicaval anastomosis technique was used since 1999. Mean follow up duration was 6.5 +/- 4.4 yr. Two patients (1%) died in-hospital due to sepsis caused by infection. Late death occurred in 39 patients (19.4%) with the most common cause being sepsis due to infection. The 1-, 5-, and 10-yr survival rates in these patients were 95.5% +/- 1.5%, 86.9% +/- 2.6%, and 73.5% +/- 4.1%, respectively. The surgical results of heart transplantation in adults were excellent, with late mortality due primarily to infection, malignancy, and rejection. Cardiac deaths related to cardiac allograft vasculopathy were very rare.
