A Case of Hydrogen Peroxide Induced Colitis.
- Author:
Seong Kwoo CHO
1
;
Young Kwan KIM
;
Young Rock LEE
;
Young Ho KIM
;
Sang Mo PARK
;
So Young KU
;
Jae Kwon KIM
;
Yeon Soo LEE
;
Kyoung Ho KIM
Author Information
1. Department of Internal Medicine, Chung Goo Sung Sim General Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Hydrogen peroxide;
Chemical colitis;
Disinfectant colitis
- MeSH:
Abdominal Pain;
Adult;
Anal Canal;
Colitis*;
Colon;
Colonoscopy;
Disinfection;
Endoscopes;
Enteritis;
Epithelium;
Erythema;
Estrogens, Conjugated (USP);
Fibrin;
Gastrointestinal Hemorrhage;
Hemorrhage;
Humans;
Hydrogen Peroxide*;
Hydrogen*;
Male;
Mucous Membrane;
Oxygen;
Ulcer;
Vacuoles
- From:Korean Journal of Gastrointestinal Endoscopy
1999;19(4):659-666
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hydrogen peroxide has been used for various medical purposes and also recommended in the disinfection process for endoscopes. However, hydrogen peroxide as a cause of chemical colitis or disinfectant colitis has been infrequently reported. The endoscopic findings of hydrogen peroxide induced colitis revealed pseudomembranous-like enteritis such as white plaques, erythema, foamy liquid, patchy, granularity, and ulcerations, resulting from effervescence caused by the release of oxygen from the breakdown of hydrogen peroxide. A 36 year-old single male, who had 30 ml of 3% hydrogen peroxide inserted into his anus the day before due to sexual reasons, was hospitalized as a result of suffering from hematochezia, tenesmus, and lower abdominal pain. Colonoscopy revealed discrete or confluent white plaques adherent to the colonic mucosa, severe erythema on the surrounding mucosa, patchy granularity, and scattered ulcerations up to 28 cm from the anal verge. Pathologic finding revealed inflammatory cells infiltration, variable sized vacuoles, vascular congestion, hemorrhage, fibrin deposition and ulcerations with regenerating epithelium in the lamina propria, consistent with acute mucosal injury caused by hydrogen peroxide. A case of hydrogen peroxide induced colitis is herein reported.
