A Case of Steroid Myopathy in Istrogenic Cushing Syndrome.
- Author:
Choong Seop SHIM
1
;
Hyoung Cheol KIM
;
Seung Hyun KIM
;
Ju Han KIM
;
Myung Ho KIM
;
You Hern AHN
;
Je Geun CHI
Author Information
1. Department of Neurology, College of Medicine, Hanyang University, Koea.
- Publication Type:Brief Communication
- MeSH:
Adenosine Triphosphatases;
Atrophy;
Biopsy;
Cushing Syndrome*;
Female;
Humans;
Hydrogen-Ion Concentration;
Inflammation;
Middle Aged;
Muscle Weakness;
Muscular Diseases*;
Needles;
Phenytoin
- From:Journal of the Korean Neurological Association
1993;11(3):467-470
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Steroid myopathy is one of the most common drug-induced myopathy. We report a case of iatrogenic steroid myopathy in a 61-year-old female who had taken herb medication more than 2 months. She presented a slowly progressive proximal muscle weakness and wasting with typical features of cushing syndrome. Needle EMG showed typical myopathic patterns. The muscle biopsy revealed a pronounced muscle fiber atrophy and fatty degenerative change without inflammation. In addition, there was a selective type 2 fiber depletion on ATPase staining in pH 9.4 buffer. Her muscle powers and bulks were slowly improved after discontinuation of herb medication with phenytoin and physical therapy.
