Pachydermoperiostosis: Trial with Isotretinoin.
10.3349/ymj.1988.29.2.204
- Author:
Yoon Kee PARK
1
;
Hyung Joo KIM
;
Kee Yang CHUNG
Author Information
1. Department of Dermatology, Yonsei University college of Medicine, Seoul, Korea.
- Publication Type:Case Report ; Clinical Trial
- Keywords:
Pachydermoperiostosis;
isotretinoin
- MeSH:
Adult;
Case Report;
Clinical Trials;
Human;
Isotretinoin/*therapeutic use;
Male;
Osteoarthropathy, Primary Hypertrophic/diagnosis/*drug therapy
- From:Yonsei Medical Journal
1988;29(2):204-207
- CountryRepublic of Korea
- Language:English
-
Abstract:
A22-year-old male patient presented with typical features of pachydermoperiostosis. Thickening and oiliness of the facial skin, clubbing of the fingers, and hyperhidrosis of the palms and soles were the most prominent features. Osteosclerosis and hypertrophic osteoarthropathy were present in the bones of the hands, feet and tibia. We administered isotretinoin with the rationale that the drug inhibits sebum and collagen production. The patient was quite satisfied with the reduction of facial oiliness.